(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid
Brand: ChemScene
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CAS No. 1260616-69-0
Cat. No. CS-0169353
Purity≥95%
MDL No.MFCD07372099

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid|CS-0169353

Structure of 1260616-69-0

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Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid is a chiral building block featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and a biphenyl-substituted alanine scaffold. This configuration enables direct incorporation into peptide synthesis workflows, offering enhanced solubility and stability under standard conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid serves as a valuable chiral building block for peptide synthesis, enabling efficient incorporation of sterically hindered arylalanine derivatives. The Fmoc group provides orthogonal protection and facile removal under mild basic conditions, while the biphenyl moiety imparts metabolic stability and structural rigidity. Bench-stable and compatible with standard coupling protocols, this amino acid derivative facilitates the construction of complex peptidomimetics and biologically active scaffolds.

General Information

CAS No. 1260616-69-0
Cat. No. CS-0169353
Purity ≥95%
MDL No. MFCD07372099
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₀H₂₅NO₄
Molecular Weight 463.52
Synonym(s) None
SMILES OC([C@H](CC1=CC(C2=CC=CC=C2)=CC=C1)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O

Computational Chemistry Data

TPSA 75.63
LogP 5.888
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 7

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid

CAS No. 1260616-69-0

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