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Structure of 1260656-87-8
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6-Bromo-2-(trifluoromethyl)oxazolo[4,5-b]pyridine is a heterocyclic building block featuring a bromo group at the 6-position and a trifluoromethyl substituent at the 2-position. This combination imparts enhanced electron-withdrawing character and improved metabolic stability, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. The scaffold serves as a key intermediate in the synthesis of functionalized pharmaceuticals and agrochemicals.
6-Bromo-2-(trifluoromethyl)oxazolo[4,5-b]pyridine serves as a versatile building block for the synthesis of functionalized heterocycles in medicinal chemistry and materials science. The bromo group enables palladium-catalyzed cross-coupling reactions, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. Its oxazolopyridine core provides a rigid, electron-deficient scaffold with favorable solubility and bench stability, facilitating efficient purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: