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Structure of 243455-57-4
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This oxazole derivative features a 3-bromophenyl group at the 5-position, enabling direct incorporation into heterocyclic scaffolds. The bromine substituent serves as a versatile handle for palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl architectures under standard conditions. The electron-deficient nature of the ring system enhances reactivity in electrophilic substitution processes.
5-(3-Bromophenyl)oxazole serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. The bromo substituent enables palladium-catalyzed cross-coupling reactions, facilitating C–C bond formation under mild conditions. Its oxazole core exhibits excellent bench stability, tolerates a range of functional groups, and simplifies purification due to low polarity. This compound functions effectively in Suzuki, Stille, and Negishi coupling protocols, offering reliable access to complex aromatic scaffolds used in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: