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Structure of 1260759-82-7
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4-Fluoro-1H-indole-3-carbonitrile features a fluorinated indole core with a nitrile group at the 3-position, enabling integration into diverse heterocyclic architectures. The electron-deficient carbonitrile and ortho-fluorine substitution enhance reactivity in cross-coupling processes and facilitate incorporation into bioactive scaffolds requiring precise electronic tuning.
4-Fluoro-1H-indole-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C3 position via nucleophilic substitution or transition-metal-catalyzed coupling. The nitrile group offers synthetic handle for amidation or reduction, while the fluorine substituent enhances metabolic stability and modulates electronic properties. Its bench-stable crystalline form facilitates handling and purification in multi-step synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: