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Structure of 23077-42-1
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4-Fluoro-1H-indole-3-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the 3-position, enabling direct incorporation into bioactive molecule scaffolds. The electron-withdrawing fluorine substituent enhances metabolic stability and modulates electronic properties for medicinal chemistry applications. This bench-stable, moisture-tolerant reagent facilitates efficient coupling reactions in peptide and heterocyclic synthesis workflows.
4-Fluoro-1H-indole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of indole-based pharmaceuticals and agrochemicals. Its carboxylic acid functionality facilitates direct coupling reactions, while the 4-fluoro substituent enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard functional group transformations, making it ideal for iterative synthesis workflows and scaffold diversification.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: