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Structure of 1260773-08-7
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This pyrazole-based scaffold integrates a trifluoromethoxy-substituted phenyl ring with a carboxylic acid handle, delivering enhanced electron-withdrawing character and improved metabolic stability. The conjugated system supports direct derivatization for bioactive molecule development.
1-(3-(Trifluoromethoxy)phenyl)-1H-pyrazole-4-carboxylic acid serves as a versatile building block for medicinal chemistry campaigns, enabling the construction of bioactive heterocyclic scaffolds. The trifluoromethoxy group enhances metabolic stability and lipophilicity, while the pyrazole core provides a rigid, hydrogen-bond-capable platform. Its carboxylic acid functionality facilitates direct derivatization or coupling reactions, offering robust utility in peptide conjugation, macrocyclization, and scaffold diversification workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: