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Structure of 1260779-54-1
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5-Bromo-1,2,3,4-tetrahydroisoquinolin-8-amine features a brominated tetrahydroisoquinoline core with a primary amine at the 8-position, enabling direct functionalization in synthetic routes. The electron-deficient aromatic system enhances reactivity in coupling reactions, while the saturated ring ensures conformational stability and improved solubility in polar solvents. This scaffold serves as a key intermediate for bioactive molecule synthesis.
5-Bromo-1,2,3,4-tetrahydroisoquinolin-8-amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through palladium-catalyzed cross-coupling reactions. The bromo group facilitates efficient functionalization, while the primary amine offers direct derivatization pathways. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses targeting CNS-active compounds and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: