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CS-W001157 4
Total: USD 88.00

3,3-Difluorocyclopentaecarboxylic acid

  • CAS No. 1260897-05-9

  • Cat. No. CS-W001377
  • Purity≥95%
  • MDL No.MFCD15526661

*For research and further manufacturing use only, not for direct human use.

3,3-Difluorocyclopentaecarboxylic acid|CS-W001377

Structure of 1260897-05-9

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General Information

  • CAS No. 1260897-05-9
  • Cat. No. CS-W001377
  • Purity ≥95%
  • MDL No. MFCD15526661
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈F₂O₂
  • Molecular Weight 150.12
  • Synonym(s) 3,3-Difluorocyclopentanecarboxylic acid
  • SMILES OC(=O)C1CCC(C1)(F)F

Description

3,3-Difluorocyclopentaecarboxylic acid features a rigid cyclopentane core with two fluorine atoms at the C3 position, imparting enhanced metabolic stability and altered electronic properties. This structural motif enables precise modulation of lipophilicity and conformational rigidity in medicinal chemistry applications, facilitating targeted interactions within biological binding sites.

Application

3,3-Difluorocyclopentaecarboxylic acid serves as a valuable building block in medicinal chemistry, offering a rigid, electron-deficient cyclopentane scaffold with enhanced metabolic stability. Its difluoro substitution pattern imparts favorable lipophilicity and bioavailability profiles, enabling efficient incorporation into bioactive molecules. The carboxylic acid group facilitates direct conjugation or derivatization via standard amide, ester, or acyl transfer reactions, supporting versatile synthetic access to fluorinated heterocycles and pharmaceutical intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.5064
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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