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Structure of 1261686-95-6
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2-(Bromomethyl)-6-fluorobenzonitrile serves as a key impurity in trelagliptin synthesis, featuring a bromomethyl group flanked by fluorine and nitrile functionalities. This configuration enables targeted incorporation into complex molecular scaffolds during pharmaceutical process development.
2-(Bromomethyl)-6-fluorobenzonitrile serves as a key synthetic intermediate in the production of Trelagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor. The molecule features a bromomethyl group adjacent to a fluorinated benzene ring and a nitrile functionality, enabling efficient late-stage functionalization via nucleophilic substitution or cross-coupling reactions. Its bench-stable nature and compatibility with standard reaction conditions facilitate reliable incorporation into complex heterocyclic scaffolds during API synthesis.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: