(αR,βR)-α,β-Diphenyl-1-piperidineethanamine

Name: (αR,βR)-α,β-Diphenyl-1-piperidineethanamine
Brand: ChemScene
Availability: InStock
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CAS No. 1262516-53-9
Cat. No. CS-0093053
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(αR,βR)-α,β-Diphenyl-1-piperidineethanamine|CS-0093053

Structure of 1262516-53-9

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Description

This chiral piperidine derivative features a rigid, sterically defined scaffold with two aryl substituents positioned at the α and β carbons, enabling precise stereocontrol in asymmetric synthesis. The (αR,βR) configuration imparts high enantioselectivity in catalytic transformations, particularly in transition-metal-mediated C–C bond formation. Its bench-stable, moisture-tolerant nature simplifies handling under standard conditions.

Application

(αR,βR)-α,β-Diphenyl-1-piperidineethanamine serves as a chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry. Its rigid, stereodefined structure enables selective functionalization and facilitates the construction of complex heterocyclic scaffolds. The molecule exhibits good bench stability and compatibility with standard coupling reactions, making it suitable for modular synthesis workflows.

General Information

CAS No. 1262516-53-9
Cat. No. CS-0093053
Purity ≥97%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₉H₂₄N₂
Molecular Weight 280.41
Synonym(s) (1R,2R)-1,2-diphenyl-2-(piperidin-1-yl)ethanamine
SMILES N[C@H](C1=CC=CC=C1)[C@@H](C2=CC=CC=C2)N3CCCCC3

Computational Chemistry Data

TPSA 29.26
LogP 3.9136
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 4

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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(αR,βR)-α,β-Diphenyl-1-piperidineethanamine

CAS No. 1262516-53-9

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