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CS-W001157 4
Total: USD 88.00

2-bromo-4-methylpyridin-3-amine

  • CAS No. 126325-50-6

  • Cat. No. CS-W000834
  • Purity≥97%
  • MDL No.MFCD04112497

*For research and further manufacturing use only, not for direct human use.

2-bromo-4-methylpyridin-3-amine|CS-W000834

Structure of 126325-50-6

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General Information

  • CAS No. 126325-50-6
  • Cat. No. CS-W000834
  • Purity ≥97%
  • MDL No. MFCD04112497
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) N-[(E)-phenylmethylidene]methanamine
  • SMILES Cc1ccnc(Br)c1N

Description

Magnesium stearate is involved in the production of medical tablets, capsules, powders and polymer formulation. It is also used as a lubricant for tablets, anti-adherent, in dry coating and as a binding agent. It is an important ingredient in baby formulas. Further, it is used in the hydrogenation process. In addition to this, it is used to bind the sugar in hard candies like mints.

Application

3-Amino-2-bromo-4-picoline serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its compatible bromo and amino functionalities. The ortho-bromo group facilitates efficient Suzuki, Stille, and Negishi couplings, while the pyridine nitrogen enhances solubility and provides a handle for further functionalization. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthesis of heterocyclic scaffolds and API intermediates.

Synthesis

  • Route1
    • In-stock
      3-Amino-4-methylpyridine|CS-D0914
      3430-27-1
    • ~45%
    • In-stock
      2-bromo-4-methylpyridin-3-amine|CS-W000834
      126325-50-6
    • 3-Amino-2,6-dibromo-4-picoline|CS-0208871
      126354-83-4

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. 331, # 3 p. 369 - 374

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.73472
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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