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Structure of 126674-78-0
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2-Amino-3,5-difluorobenzoic acid delivers a trifunctional scaffold featuring an electron-rich amine, two fluorine substituents at meta positions, and a carboxylic acid for conjugation. This combination enables direct incorporation into bioconjugation workflows, peptide synthesis, and medicinal chemistry campaigns requiring enhanced metabolic stability and targeted electronic modulation.
2-Amino-3,5-difluorobenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocycles and bioactive scaffolds. Its ortho-amino and difluorinated aromatic core provides enhanced metabolic stability and modulated electronic properties. The carboxylic acid group facilitates direct coupling reactions, while the amino functionality supports derivatization via acylation, sulfonylation, or diazotization. Bench-stable and readily purified by recrystallization, it functions effectively in standard peptide coupling and transition-metal-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: