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Structure of 1268142-04-6
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3-(3-Bromophenyl)piperidine-2,6-dione features a brominated phenyl group attached to a piperidine-2,6-dione core, delivering enhanced electron-withdrawing character and structural rigidity. This scaffold serves as a high-value intermediate in medicinal chemistry campaigns targeting CNS modulators and kinase inhibitors. The bromine substituent enables further diversification via cross-coupling reactions, while the diketone framework supports chelation and conformational control. Bench-stable under standard conditions, it integrates efficiently into multi-step synthesis workflows.
3-(3-Bromophenyl)piperidine-2,6-dione serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted piperidinones and fused ring systems. Its brominated aryl group facilitates palladium-catalyzed coupling reactions, while the diketone functionality supports sequential functionalization and cyclization. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for iterative synthetic strategies in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: