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Structure of 1268810-17-8
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1-Ethynylcyclopropan-1-amine hydrochloride features a strained cyclopropyl ring fused to an ethynyl group and a protonated amine, delivering high reactivity in click chemistry. This bench-stable, moisture-tolerant derivative enables efficient coupling under mild conditions, facilitating rapid access to functionalized scaffolds in medicinal chemistry and chemical biology applications.
1-Ethynylcyclopropan-1-amine hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles and functionalized alkynes. Its cyclopropyl scaffold imparts structural rigidity, while the terminal alkyne and amine functionalities enable diverse coupling reactions, including copper-catalyzed azide-alkyne cycloadditions (CuAAC) and nucleophilic substitutions. The hydrochloride salt enhances bench stability and facilitates purification, making it suitable for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: