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Structure of 1270356-25-6
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5-Bromo-2-(piperidin-2-yl)pyridine features a brominated pyridine core paired with a piperidinyl substituent, enabling efficient coupling in cross-coupling reactions. The electron-deficient aromatic ring facilitates transition-metal catalysis, while the pendant piperidine offers solubility and coordination potential. This compound serves as a key building block in medicinal chemistry for targeted heterocyclic scaffolds.
5-Bromo-2-(piperidin-2-yl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biaryl and heteroaryl scaffolds. The bromide functionality offers high reactivity in Suzuki, Stille, and Negishi couplings, while the piperidinyl group provides a basic nitrogen for metal coordination and potential hydrogen bonding in target molecules. Bench-stable and readily purified by column chromatography, it facilitates efficient synthesis of complex pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: