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Structure of 127510-96-7
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Methyl 2-cyano-4-fluorobenzoate features a strategically positioned cyano and fluorine substituent on the aromatic ring, delivering enhanced electron-withdrawing character and improved metabolic stability. This combination enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds. The ester functionality supports further derivatization under standard conditions.
Methyl 2-cyano-4-fluorobenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated heterocycles and bioactive scaffolds. Its dual functionality—cyano and ester groups—facilitates sequential transformations, including nucleophilic addition, reduction, and cyclization reactions. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, allowing straightforward purification and integration into multi-step synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: