Lenalidomide-5-Br

Name: Lenalidomide-5-Br
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1010100-26-1
Cat. No. CS-0105752
Purity≥97%
MDL No.MFCD32263142

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HazMat Fee

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1010100-26-1

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Description

Lenalidomide-5-Br features a bromine substitution at the 5-position of the phthalimide ring, enhancing its reactivity in cross-coupling processes. This derivative serves as a key intermediate for diversifying imide-based pharmaceuticals, offering improved functional group compatibility under standard coupling conditions.

Application

Lenalidomide-5-Br serves as a versatile brominated derivative enabling site-specific functionalization in the development of immunomodulatory drug analogs. The bromine substituent at the 5-position facilitates palladium-catalyzed cross-coupling reactions, supporting efficient diversification of the imidazoline core. Its bench-stable nature and compatibility with standard synthetic protocols make it a practical building block for medicinal chemistry campaigns targeting targeted protein degradation and immune modulation.

General Information

CAS No. 1010100-26-1
Cat. No. CS-0105752
Purity ≥97%
MDL No. MFCD32263142
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₃H₁₁BrN₂O₃
Molecular Weight 323.15
Synonym(s) None
SMILES O=C(C(N(CC1=C2C=CC(Br)=C1)C2=O)CC3)NC3=O

Computational Chemistry Data

TPSA 66.48
LogP 0.6642
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Life Science PROTAC Ligands for E3 Ligase

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Proteolysis Targeting Chimera Research Reagents

Biochemistry Pharmaceutical Development and Drug Discovery Research Proteolysis Targeting Chimera Research Reagents

Key Words

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Lenalidomide-5-Br

CAS No. 1010100-26-1

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