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Structure of 1283720-60-4
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This bench-stable thiazole derivative features a trifluoromethyl group enhancing electron-withdrawal and a methyl substituent optimizing steric profile. The pendant primary amine enables direct coupling in medicinal chemistry, serving as a key scaffold for kinase inhibitors and bioactive heterocycles.
(2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanamine serves as a versatile building block for medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the primary amine facilitates conjugation in standard coupling reactions. The compound exhibits bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for iterative synthesis and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: