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Structure of 128502-56-7
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This tetrahydroisoquinoline derivative features a hydroxyl group at the 7-position and a carboxylic acid at C3, with stereochemistry defined at the 3S center. The scaffold integrates a phenolic moiety and a chiral carboxylic acid, enabling use in bioactive molecule synthesis. Bench-stable and moisture-tolerant, it serves as a key building block for alkaloid-inspired pharmaceuticals and chemical probes.
7-Hydroxy-(3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid serves as a key chiral building block for the synthesis of bioactive isoquinoline derivatives. Its well-defined stereochemistry at C3 and orthogonal functional groups enable reliable derivatization via amide coupling, esterification, or electrophilic substitution. The molecule exhibits good bench stability and facilitates efficient purification, making it suitable for medicinal chemistry campaigns targeting CNS-active compounds and natural product analogs.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: