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(1R,2R)-1-Aminoindan-2-ol

  • CAS No. 163061-73-2

  • Cat. No. CS-0147141
  • Molecule weight149.19
  • Purity≥98%
  • MDL No.MFCD08275447

*For research and further manufacturing use only, not for direct human use.

(1R,2R)-1-Aminoindan-2-ol|CS-0147141

Structure of 163061-73-2

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General Information

  • CAS No. 163061-73-2
  • Cat. No. CS-0147141
  • Purity ≥98%
  • MDL No. MFCD08275447
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO
  • Molecular Weight 149.19
  • Synonym(s) None
  • SMILES O[C@H]1[C@@H](C2=C(C1)C=CC=C2)N

Application

(1R,2R)-1-Aminoindan-2-ol serves as a stereochemically defined chiral building block for the synthesis of biologically active compounds. Its rigid indane scaffold with proximal amine and hydroxyl groups enables selective functionalization and facilitates hydrogen bonding in target-directed design. The compound exhibits bench stability and compatibility with standard protecting group strategies, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • rel-(1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol|CS-0147143
      7480-35-5
    • ~%
    • In-stock
      (1R,2R)-1-Aminoindan-2-ol|CS-0147141
      163061-73-2
    • In-stock
      (1S,2S)-(+)-1-Amino-2-indanol|CS-0034926
      163061-74-3

    References

    • Analytical Chemistry, , vol. 81, # 24 p. 10215 - 10226
  • Route2
    • null|null
      945950-53-8
    • ~%
    • In-stock
      (1R,2R)-1-Aminoindan-2-ol|CS-0147141
      163061-73-2

    References

    • Tetrahedron Asymmetry, , vol. 22, # 24 p. 2134 - 2143
  • Route3
    • rel-(1R,2S)-1-Amino-2,3-dihydro-1H-inden-2-ol|CS-0147143
      7480-35-5
    • ~%
    • In-stock
      (1R,2R)-1-Aminoindan-2-ol|CS-0147141
      163061-73-2

    References

    • Tetrahedron Asymmetry, , vol. 22, # 24 p. 2134 - 2143

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.6034
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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