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CS-W001157 4
Total: USD 88.00

THP-PEG4-OH

  • CAS No. 128660-97-9

  • Cat. No. CS-0105845
  • Purity≥95%
  • MDL No.MFCD26127805
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

THP-PEG4-OH|CS-0105845

Structure of 128660-97-9

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Description

THP-PEG4-OH is a bench-stable, moisture-tolerant protecting group for hydroxyl functionalities, featuring a tetrahydropyranyl moiety linked via a four-ethylene glycol spacer. This configuration enables selective protection in complex synthesis while offering facile deprotection under mild acidic conditions. The terminal primary alcohol facilitates conjugation and further derivatization in bioconjugation workflows.

Application

THP-PEG4-OH serves as a versatile, bench-stable protecting group for hydroxyl functionalities in complex molecule synthesis. Its tetrahydropyranyl (THP) moiety enables selective protection under mild acidic conditions, while the PEG4 linker provides enhanced solubility and compatibility with aqueous/organic media. The terminal OH group facilitates further functionalization or conjugation, making it ideal for modular assembly of peptide- and nucleotide-based constructs.

General Information

  • CAS No. 128660-97-9
  • Cat. No. CS-0105845
  • Purity ≥95%
  • MDL No. MFCD26127805
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₆O₆
  • Molecular Weight 278.34
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOC1CCCCO1

Computational Chemistry Data

  • TPSA   66.38
  • LogP   0.5717
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   12

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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