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Structure of 1287660-82-5
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Propargyl-PEG2-bromide enables efficient copper-free click chemistry through its terminal alkyne and reactive bromide handle. This bifunctional reagent integrates seamlessly into bioconjugation workflows, offering rapid conjugation with azide-bearing molecules under physiological conditions. The short PEG spacer provides enhanced solubility and reduced steric hindrance, improving reaction kinetics and yield in complex biological environments.
Propargyl-PEG2-bromide serves as a versatile bifunctional linker for bioconjugation and polymer synthesis. The terminal alkyne enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the bromide group facilitates nucleophilic substitution with amines or thiols. Its PEG2 spacer provides enhanced solubility and reduced aggregation, making it ideal for modular synthesis of functionalized biomolecules and responsive materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P301+P310-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362+P364-P501
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Lot numbers can be found on the outside label of a product: