(R)-4,5,6,7-Tetrahydro-2H-indazol-5-amine hydrochloride

Name: (R)-4,5,6,7-Tetrahydro-2H-indazol-5-amine hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1291790-29-8
Cat. No. CS-0199740
Purity≥97%
MDL No.MFCD18909649

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-4,5,6,7-Tetrahydro-2H-indazol-5-amine hydrochloride|CS-0199740

Structure of 1291790-29-8

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Description

This bench-stable (R)-4,5,6,7-tetrahydro-2H-indazol-5-amine hydrochloride features a chiral indazoline core with enhanced solubility and stability under standard conditions. The protonated amine facilitates efficient coupling in synthetic workflows, while the saturated heterocyclic framework supports selective functionalization in medicinal chemistry applications.

Application

(R)-4,5,6,7-Tetrahydro-2H-indazol-5-amine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to indazoline-based scaffolds. Its well-defined stereochemistry and amine functionality facilitate straightforward derivatization, including amidation and reductive amination. The hydrochloride salt enhances solubility and stability for handling, making it ideal for high-throughput synthesis and structure-activity studies.

General Information

CAS No. 1291790-29-8
Cat. No. CS-0199740
Purity ≥97%
MDL No. MFCD18909649
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₂ClN₃
Molecular Weight 173.64
Synonym(s) (R)-4,5,6,7-Tetrahydro-1H-indazol-5-amine hydrochloride
SMILES N[C@H]1CC2=CNN=C2CC1.Cl

Computational Chemistry Data

TPSA 54.7
LogP 0.6475
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-4,5,6,7-Tetrahydro-2H-indazol-5-amine hydrochloride

CAS No. 1291790-29-8

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