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Structure of 1294009-25-8
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This boronate reagent features a (E)-configured styryl group conjugated to a trifluoromethyl substituent, enabling efficient cross-coupling in palladium-catalyzed reactions. The tetramethyl-substituted dioxaborolane ring enhances stability and solubility, while the electron-deficient trifluoromethyl moiety promotes reactivity. This structure facilitates direct incorporation into complex molecular architectures under mild conditions.
(E)-4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)styryl)-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. Its (E)-configured styrenyl moiety enables efficient Suzuki-Miyaura coupling with aryl and heteroaryl halides, offering high functional group tolerance and predictable stereochemical retention. The tetramethyl-substituted dioxaborolane ring enhances stability and simplifies purification, making it well-suited for iterative synthesis of complex biaryls and pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: