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1-N-Boc-piperazine-3-carboxylic acid methyl ester

  • CAS No. 129799-08-2

  • Cat. No. CS-D0654
  • Molecule weight244.29
  • Purity≥96%
  • MDL No.MFCD01632465

*For research and further manufacturing use only, not for direct human use.

1-N-Boc-piperazine-3-carboxylic acid methyl ester|CS-D0654

Structure of 129799-08-2

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General Information

  • CAS No. 129799-08-2
  • Cat. No. CS-D0654
  • Purity ≥96%
  • MDL No. MFCD01632465
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀N₂O₄
  • Molecular Weight 244.29
  • Synonym(s) Piperazine-1,3-Dicarboxylic Acid 1-Tert-Butyl Ester 3-Methyl Ester
  • SMILES O=C(OC(C)(C)C)N1CC(NCC1)C(OC)=O

Description

DODAC is a cationic lipid with a pair of unsaturated tails. This complex can serve as a well-defined intermediate in the preparation of DNA-lipid particles (DLPs) with many potential applications for delivery of polynucleotides in vitro and in vivo. Reagent grade, for research use only.

Synthesis

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    References

    • ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.; BRANCA, Danila; FERRIGNO, Federica; HERNANDO, Jose, Ignacio, Martin; JONES, Philip; KINZEL, Olaf; MALANCONA, Savina; MURAGLIA, Ester; PALUMBI, Maria, Cecilia; PESCATORE, Giovanna; SCARPELLI, Rita Patent: WO2010/23480 A1, 2010 ; Location in patent: Page/Page column 44 ;
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    References

    • US4997836 A1, ;
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    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 23 p. 4241 - 4244

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   67.87
  • LogP   0.3683
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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