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Structure of 438631-77-7
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This chiral building block features a Boc-protected piperazine core with a methyl ester-functionalized carboxylic acid, enabling direct incorporation into peptide and macrocyclic scaffolds. The (R)-stereochemistry ensures high diastereoselectivity in downstream conjugations, while the bench-stable, moisture-tolerant nature simplifies handling under standard conditions.
(R)-1-N-Boc-piperazine-3-carboxylic acid methyl ester serves as a versatile chiral building block for the synthesis of piperazinyl-containing scaffolds. Its Boc-protected amine and ester functionalities enable sequential functionalization, facilitating coupling reactions and selective deprotection. The molecule exhibits excellent bench stability and simplifies purification in multi-step syntheses, making it well-suited for medicinal chemistry campaigns targeting CNS agents and kinase inhibitors.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: