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Structure of 1302580-98-8
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This cyclopropanecarboxylic acid features a 5-fluoropyridin-2-yl substituent, offering enhanced electron-withdrawing character and improved metabolic stability. The strained cyclopropane ring imparts rigidity, facilitating precise spatial orientation in synthetic intermediates. Ideal for medicinal chemistry applications requiring targeted bioavailability and structural precision.
1-(5-Fluoropyridin-2-yl)cyclopropanecarboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds. Its cyclopropane carboxylic acid motif offers enhanced metabolic stability and conformational rigidity, while the 5-fluoropyridin-2-yl group provides favorable electronic properties for coupling reactions. The compound exhibits good bench stability, facilitates efficient derivatization via standard amide bond formation, and demonstrates compatibility with diverse functional groups, making it well-suited for high-throughput synthesis campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: