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Structure of 1303588-27-3
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7-Chloro-1,2,3,4-tetrahydro-1,8-naphthyridine is a heterocyclic scaffold featuring a chlorine substituent at the 7-position, enhancing electron deficiency and enabling selective reactivity in synthetic transformations. This bench-stable, moisture-tolerant core integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
7-Chloro-1,2,3,4-tetrahydro-1,8-naphthyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. The chlorine substituent facilitates nucleophilic displacement and palladium-catalyzed coupling reactions, while the saturated pyridine core offers favorable metabolic stability and solubility. Its bench-stable nature and compatibility with diverse functional groups make it ideal for iterative synthesis of drug candidates and agrochemical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: