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Structure of 3435-25-4
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4-Chloro-6-methylpyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, featuring a chlorine atom at the 4-position and a methyl group at the 6-position. This combination imparts enhanced electronic modulation and metabolic stability, enabling efficient integration into kinase inhibitors and antiviral agents. The compound exhibits excellent bench stability and compatibility with diverse coupling reactions.
4-Chloro-6-methylpyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyrimidine-based scaffolds through palladium-catalyzed cross-coupling reactions. Its chlorine atom facilitates nucleophilic substitution under mild conditions, while the methyl group provides steric and electronic modulation. The compound exhibits excellent bench stability and is compatible with diverse functional groups, simplifying purification and scale-up in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: