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CS-W001157 4
Total: USD 88.00

2-(2-Iodoethoxy)ethan-1-ol

  • CAS No. 130536-69-5

  • Cat. No. CS-0139452
  • Purity≥95%
  • MDL No.MFCD20415309

*For research and further manufacturing use only, not for direct human use.

2-(2-Iodoethoxy)ethan-1-ol|CS-0139452

Structure of 130536-69-5

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General Information

  • CAS No. 130536-69-5
  • Cat. No. CS-0139452
  • Purity ≥95%
  • MDL No. MFCD20415309
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₉IO₂
  • Molecular Weight 216.02
  • Synonym(s) None
  • SMILES ICCOCCO

Description

2-(2-Iodoethoxy)ethanol is a reactive ether alcohol featuring a terminal iodide for facile conjugation. This bifunctional molecule combines a hydrophilic ethylene glycol chain with a potent electrophilic iodine handle, enabling efficient coupling in bioconjugation and polymer functionalization. The pendant hydroxyl group supports further derivatization while enhancing solubility in aqueous systems.

Application

2-(2-Iodoethoxy)ethanol serves as a versatile bifunctional building block for C–O and C–C bond formation, enabling efficient coupling reactions in medicinal chemistry and materials synthesis. Its iodide group facilitates palladium-catalyzed cross-coupling, while the terminal hydroxyl supports derivatization or protection. The molecule exhibits good bench stability and is readily purified by distillation, making it suitable for scalable applications in API and heterocyclic scaffold construction.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H312-H315-H318-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.4303
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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