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Structure of 1305711-34-5
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4-Methoxy-1-methyl-1H-indazol-3-amine features a fused bicyclic indazole core bearing a methoxy group at the 4-position and a methylamino substituent at the 3-position. This electron-rich scaffold integrates readily into kinase inhibitor scaffolds and offers enhanced solubility compared to analogs lacking polar functionalities.
4-Methoxy-1-methyl-1H-indazol-3-amine serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. Its structure features a substituted indazole core with orthogonal functional groups enabling direct coupling reactions, including Pd-catalyzed cross-couplings and amide bond formations. The methoxy and methyl substituents enhance solubility and metabolic stability, while the primary amine facilitates derivatization. This compound demonstrates bench stability and ease of purification, making it well-suited for scalable synthesis of kinase inhibitors and other bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: