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Structure of 131052-46-5
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Thiazol-5-ylmethanamine hydrochloride features a thiazole ring fused to a methanamine handle, delivering a robust scaffold for medicinal chemistry. This bench-stable derivative integrates readily into bioactive molecules, leveraging its nitrogen-rich heterocycle for enhanced binding affinity and metabolic stability in target-directed synthesis.
Thiazol-5-ylmethanamine hydrochloride serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. Its primary amine functionality enables straightforward functionalization, including amidation, alkylation, and coupling reactions. The thiazole core imparts metabolic stability and favorable pharmacophoric properties, making it valuable in the construction of kinase inhibitors and other bioactive scaffolds. Bench-stable and readily purified via recrystallization, it functions efficiently in standard amine transformations under mild conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: