Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(Difluoromethyl)cyclopropane-1-carboxylic acid

  • CAS No. 1314397-71-1

  • Cat. No. CS-0094849
  • Purity≥95%
  • MDL No.MFCD20230593

*For research and further manufacturing use only, not for direct human use.

1-(Difluoromethyl)cyclopropane-1-carboxylic acid|CS-0094849

Structure of 1314397-71-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1314397-71-1
  • Cat. No. CS-0094849
  • Purity ≥95%
  • MDL No. MFCD20230593
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆F₂O₂
  • Molecular Weight 136.10
  • Synonym(s) 1-(difluoromethyl)cyclopropanecarboxylic acid
  • SMILES O=C(C1(C(F)F)CC1)O

Description

1-(Difluoromethyl)cyclopropane-1-carboxylic acid features a strained cyclopropane ring fused to a difluoromethyl group, delivering enhanced metabolic stability and lipophilicity. This structural motif enables robust incorporation into bioactive molecules, particularly in medicinal chemistry scaffolds targeting CNS disorders and enzyme inhibition. The carboxylic acid functionality facilitates direct derivatization or salt formation for improved solubility and handling.

Application

1-(Difluoromethyl)cyclopropane-1-carboxylic acid serves as a valuable building block in medicinal chemistry, offering a rigid cyclopropyl scaffold with a metabolically stable difluoromethyl group. The carboxylic acid functionality enables straightforward derivatization via esterification, amide coupling, or decarboxylation protocols. Its bench-stable nature and compatibility with diverse reaction conditions facilitate integration into synthetic routes for bioactive molecules and heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.1163
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1314397-71-1 sigma1314397-71-1 manufacturer1314397-71-1 price1314397-71-1 structure1314397-71-1 SDSbuy 1314397-71-11314397-71-1 supplier1314397-71-1 uses1314397-71-1 molecular weightprice of 1314397-71-11314397-71-1 chemical name formula of 1314397-71-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label