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Structure of 532391-89-2
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This bench-stable heterocyclic carboxylic acid features a fused oxazine ring system with a methyl substituent at the 4-position, enhancing electronic delocalization. The para-carboxyl group enables direct coupling in peptide synthesis and medicinal chemistry scaffolds.
4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its fused oxazine scaffold provides structural rigidity and favorable pharmacokinetic properties, while the carboxylic acid functionality enables facile derivatization via amide coupling, esterification, or salt formation. The methyl group enhances metabolic stability and modulates lipophilicity. Bench-stable and compatible with standard synthetic protocols, it facilitates efficient access to diverse analogs in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: