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Structure of 1314397-71-1
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1-(Difluoromethyl)cyclopropane-1-carboxylic acid features a strained cyclopropane ring fused to a difluoromethyl group, delivering enhanced metabolic stability and lipophilicity. This structural motif enables robust incorporation into bioactive molecules, particularly in medicinal chemistry scaffolds targeting CNS disorders and enzyme inhibition. The carboxylic acid functionality facilitates direct derivatization or salt formation for improved solubility and handling.
1-(Difluoromethyl)cyclopropane-1-carboxylic acid serves as a valuable building block in medicinal chemistry, offering a rigid cyclopropyl scaffold with a metabolically stable difluoromethyl group. The carboxylic acid functionality enables straightforward derivatization via esterification, amide coupling, or decarboxylation protocols. Its bench-stable nature and compatibility with diverse reaction conditions facilitate integration into synthetic routes for bioactive molecules and heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: