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Structure of 1315355-92-0
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Mal-amido-PEG5-C2-NHS ester features a maleimide group conjugated to a PEG5 spacer with a C2 linker, enabling site-specific bioconjugation via thiol-reactive addition. The NHS ester moiety facilitates efficient coupling to primary amines under physiological conditions. This bifunctional reagent streamlines the creation of stable protein-drug conjugates and targeted delivery systems.
Mal-amido-PEG5-C2-NHS ester serves as a versatile bifunctional crosslinker, enabling efficient conjugation of biomolecules via amine and thiol groups. The NHS ester reacts selectively with primary amines under physiological conditions, while the maleimide moiety rapidly engages cysteine thiols through Michael addition. This PEG5 spacer provides enhanced solubility and reduced non-specific binding, making it ideal for antibody-drug conjugates, protein labeling, and bioconjugation workflows requiring site-specific modification and improved stability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: