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Structure of 1315364-91-0
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5-Chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid delivers a rigid, electron-deficient heterocyclic scaffold ideal for medicinal chemistry applications. This compound integrates a chlorinated pyrazolopyrimidine core with a carboxylic acid handle, enabling direct conjugation or derivatization in target-oriented synthesis. The structure supports hydrogen bonding and π-stacking interactions, enhancing binding affinity in kinase inhibitor design.
5-Chloropyrazolo[1,5-a]pyrimidine-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its ortho-chloro and carboxylic acid functionalities enable direct derivatization via amide coupling, Suzuki-Miyaura cross-coupling, or nucleophilic substitution. The scaffold exhibits bench stability and facilitates purification by recrystallization, making it well-suited for high-throughput synthesis of kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: