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CS-W001157 4
Total: USD 88.00

2,2-Dimethoxypropan-1-amine

  • CAS No. 131713-50-3

  • Cat. No. CS-0147461
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,2-Dimethoxypropan-1-amine|CS-0147461

Structure of 131713-50-3

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General Information

  • CAS No. 131713-50-3
  • Cat. No. CS-0147461
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃NO₂
  • Molecular Weight 119.16
  • Synonym(s) Benzyl 3-bromo-2-oxopropylcarbamate
  • SMILES CC(OC)(OC)CN

Description

2,2-Dimethoxypropan-1-amine serves as a stable, moisture-tolerant amine building block featuring a protected primary amine group. The dimethoxypropane scaffold provides enhanced solubility and resistance to oxidation, enabling straightforward incorporation into peptide mimetics and bioactive small molecules under standard conditions.

Application

2,2-Dimethoxypropan-1-amine serves as a stable, bench-ready amine building block for the synthesis of bioactive heterocycles and peptide mimetics. Its dimethyl acetal functionality enables orthogonal protection of aldehydes and facilitates reductive amination workflows. The molecule exhibits excellent functional group tolerance, simplifies purification, and functions effectively in standard coupling and cyclization protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   -0.0459
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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