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Structure of 131747-55-2
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2-Fluoro-3-(hydroxymethyl)pyridine features a strategically positioned fluorine atom and a reactive hydroxymethyl group, enabling direct functionalization in synthetic transformations. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and ligand scaffolds, offering enhanced solubility and metabolic stability under standard conditions.
2-Fluoro-3-(hydroxymethyl)pyridine serves as a versatile pyridine-based building block for medicinal chemistry and catalytic synthesis. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the hydroxymethyl group provides a handle for derivatization via oxidation, protection, or coupling reactions. This compound exhibits good bench stability and functional group tolerance, facilitating its use in multistep syntheses of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: