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CS-W001157 4
Total: USD 88.00

2-Fluoro-3-(hydroxymethyl)pyridine

  • CAS No. 131747-55-2

  • Cat. No. CS-D0977
  • Purity≥98%
  • MDL No.MFCD03092920
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

2-Fluoro-3-(hydroxymethyl)pyridine|CS-D0977

Structure of 131747-55-2

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Description

2-Fluoro-3-(hydroxymethyl)pyridine features a strategically positioned fluorine atom and a reactive hydroxymethyl group, enabling direct functionalization in synthetic transformations. This electron-deficient heterocycle integrates readily into pharmaceutical intermediates and ligand scaffolds, offering enhanced solubility and metabolic stability under standard conditions.

Application

2-Fluoro-3-(hydroxymethyl)pyridine serves as a versatile pyridine-based building block for medicinal chemistry and catalytic synthesis. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the hydroxymethyl group provides a handle for derivatization via oxidation, protection, or coupling reactions. This compound exhibits good bench stability and functional group tolerance, facilitating its use in multistep syntheses of heterocyclic scaffolds and API intermediates.

General Information

  • CAS No. 131747-55-2
  • Cat. No. CS-D0977
  • Purity ≥98%
  • MDL No. MFCD03092920
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆FNO
  • Molecular Weight 127.12
  • Synonym(s) 3-Pyridinemethanol,2-fluoro-(9CI)
  • SMILES OCC1=CC=CN=C1F

Computational Chemistry Data

  • TPSA   33.12
  • LogP   0.713
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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