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Structure of 131858-37-2
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4-(Bromomethyl)-2-fluoro-1-nitrobenzene features a reactive bromomethyl group flanked by electron-withdrawing fluorine and nitro substituents, enabling efficient coupling in cross-coupling and bioconjugation workflows. The ortho-fluoro substitution enhances regioselectivity, while the bench-stable aryl halide resists premature decomposition under standard conditions.
4-(Bromomethyl)-2-fluoro-1-nitrobenzene serves as a versatile bifunctional building block for C–C and C–heteroatom bond formation. The bromomethyl group enables palladium-catalyzed cross-coupling reactions, while the ortho-fluoro and para-nitro substituents provide orthogonal reactivity for selective functionalization. Its bench-stable nature and compatibility with common protecting groups facilitate efficient synthesis of complex aryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: