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Structure of 446-34-4
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5-Methyl-2-nitrofluorobenzene features a strategically positioned nitro group and methyl substituent that enhance electrophilic reactivity in transition metal-catalyzed cross-coupling reactions. This electron-deficient aryl fluoride integrates readily into complex molecular architectures, offering high stability under standard conditions and compatibility with diverse reaction setups.
5-Methyl-2-nitrofluorobenzene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive aryl fluoride functionality. The ortho-nitro and methyl groups provide regiochemical control and enhance electrophilic reactivity, while the compound exhibits good bench stability and compatibility with standard purification methods. Its structure facilitates efficient access to substituted heterocycles and functionalized aromatic scaffolds commonly encountered in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: