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Structure of 1319255-36-1
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This difluoromethyl-substituted thiazole features a bromine atom at the 5-position, enabling direct functionalization in cross-coupling reactions. The electron-deficient heterocyclic core, combined with the fluorinated side chain, enhances metabolic stability and modulates lipophilicity for medicinal chemistry applications.
5-Bromo-2-(difluoromethyl)-1,3-thiazole serves as a versatile building block for the synthesis of fluorinated heterocycles and pharmaceutical intermediates. The bromine substituent enables palladium-catalyzed cross-coupling reactions, while the difluoromethyl group imparts metabolic stability and modulates electronic properties. This compound exhibits excellent bench stability, facilitates straightforward purification, and demonstrates broad functional group tolerance in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501
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Lot numbers can be found on the outside label of a product: