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Structure of 57268-16-3
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5-Bromo-2-methylthiazole is a heterocyclic building block featuring a brominated thiazole core with a methyl substituent at the 2-position. This configuration imparts enhanced reactivity in cross-coupling transformations and facilitates selective functionalization. The molecule exhibits excellent stability under standard conditions, enabling reliable integration into complex synthetic sequences. Its compatibility with palladium-catalyzed reactions supports efficient access to diverse thiazole-based architectures.
5-Bromo-2-methylthiazole serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the 5-position via palladium-catalyzed cross-coupling reactions. Its methyl group enhances regiochemical control in electrophilic substitution, while the bromine facilitates coupling with aryl, vinyl, and alkynyl partners. Bench-stable and readily purified by flash chromatography, it functions effectively in the construction of biologically relevant thiazole scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: