5-Amino-8-hydroxyquinoline

Name: 5-Amino-8-hydroxyquinoline
Brand: ChemScene
Availability: OutOfStock
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CAS No. 13207-66-4
Cat. No. CS-W001023
Purity≥95%
MDL No.MFCD00185837

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Description

5-Amino-8-hydroxyquinoline delivers a dual functional handle for coordination chemistry and molecular synthesis. The amino group enables nucleophilic coupling, while the hydroxyquinoline scaffold provides a rigid, electron-rich platform for metal chelation. This compound exhibits enhanced solubility in polar solvents and maintains stability under standard bench conditions, facilitating its use in ligand design and fluorescent probe development.

Application

5-Amino-8-hydroxyquinoline serves as a versatile scaffold in medicinal chemistry and coordination chemistry, enabling efficient metal chelation and serving as a building block for heterocyclic derivatives. Its dual functionality—amine and phenolic hydroxyl groups—facilitates selective derivatization, orthogonally protected transformations, and integration into bioactive molecules. The compound exhibits bench stability and ease of purification, supporting its use in multi-step synthesis and high-throughput screening campaigns.

General Information

CAS No. 13207-66-4
Cat. No. CS-W001023
Purity ≥95%
MDL No. MFCD00185837
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₈N₂O
Molecular Weight 160.18
Synonym(s) 5A8HQ; 5AHQ
SMILES NC1=C2C=CC=NC2=C(O)C=C1

Computational Chemistry Data

TPSA 59.14
LogP 1.5226
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Phenol

Building Blocks Skeleton Aromatic heterocycle compounds quinoline compounds

Key Words

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5-Amino-8-hydroxyquinoline

CAS No. 13207-66-4

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