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Structure of 132213-07-1
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6-(Hydroxymethyl)imidazo[1,2-a]pyridine features a polar hydroxymethyl group appended to an electron-rich imidazo[1,2-a]pyridine core, enabling facile derivatization and enhanced solubility in polar solvents. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and CNS-penetrant drug candidates, offering a stable, bench-ready platform for molecular diversification.
6-(Hydroxymethyl)imidazo[1,2-a]pyridine serves as a versatile building block for heterocyclic synthesis, enabling efficient functionalization at the C6 position. The hydroxymethyl group facilitates oxidation to carboxylic acid, reductive amination, or ether formation, while the imidazo[1,2-a]pyridine core exhibits favorable stability and compatibility with standard coupling reactions. Its well-defined reactivity profile supports reliable incorporation into pharmaceutical intermediates and advanced synthetic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: