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CS-W001157 4
Total: USD 88.00

(4r)-4-(Hydroxymethyl)-1,3-oxazolidin-2-one

  • CAS No. 132682-23-6

  • Cat. No. CS-0216909
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4r)-4-(Hydroxymethyl)-1,3-oxazolidin-2-one|CS-0216909

Structure of 132682-23-6

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General Information

  • CAS No. 132682-23-6
  • Cat. No. CS-0216909
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₃
  • Molecular Weight 117.10
  • Synonym(s) (R)-4-(Hydroxymethyl)oxazolidin-2-one
  • SMILES O=C1N[C@@H](CO1)CO

Description

This oxazolidinone derivative features a chiral (4R) center and a hydroxymethyl group, enabling selective functionalization in asymmetric synthesis. The cyclic carbamate structure provides stability and compatibility with diverse reaction conditions, facilitating integration into complex molecular architectures.

Application

(4R)-4-(Hydroxymethyl)-1,3-oxazolidin-2-one serves as a versatile chiral building block in synthetic organic chemistry, enabling stereoselective transformations through its pendant hydroxyl and lactam functionalities. It functions as a protected amino alcohol equivalent, offering stability and compatibility with common coupling and reduction protocols. Its well-defined stereochemistry facilitates incorporation into complex heterocyclic systems and peptide-like scaffolds, supporting efficient synthesis of bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.9129
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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