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Structure of 36052-27-4
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Methyl 3-aminopicolinate features a pyridine ring bearing both methyl ester and primary amine functionalities at adjacent positions. This dual-functionalized scaffold enables direct incorporation into diverse synthetic sequences, including peptide conjugation and transition-metal-catalyzed coupling reactions. The electron-rich aromatic core supports efficient derivatization under mild conditions, while the amine group facilitates salt formation and purification.
Methyl 3-aminopicolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based pharmacophores. The ortho-amino and ester functionalities offer complementary reactivity for derivatization—enabling amide coupling, electrophilic substitution, or metal-catalyzed cross-coupling—while maintaining bench stability and ease of purification. Its structural motif is frequently encountered in API scaffolds requiring nitrogen-rich heterocyclic frameworks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: