Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Cyclobutylpiperazine

  • CAS No. 132800-13-6

  • Cat. No. CS-0038572
  • Purity≥95%
  • MDL No.MFCD06254806

*For research and further manufacturing use only, not for direct human use.

1-Cyclobutylpiperazine|CS-0038572

Structure of 132800-13-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 132800-13-6
  • Cat. No. CS-0038572
  • Purity ≥95%
  • MDL No. MFCD06254806
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆N₂
  • Molecular Weight 140.23
  • Synonym(s) N-cyc-Bu-piperazine
  • SMILES C1CC(C1)N2CCNCC2

Description

1-Cyclobutylpiperazine is a sterically constrained piperazine derivative featuring a cyclobutyl group that imparts enhanced lipophilicity and conformational rigidity. This structural profile supports improved membrane permeability and metabolic stability, making it a valuable scaffold in medicinal chemistry for CNS-targeted compounds and bioactive molecule design.

Application

1-Cyclobutylpiperazine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amine functionalization. Its cyclobutyl substitution imparts enhanced metabolic stability and favorable lipophilicity profiles compared to simpler alkylated piperazines. The molecule exhibits robust bench stability, facilitates straightforward purification, and tolerates a broad range of reaction conditions, making it well-suited for iterative synthesis workflows in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   15.27
  • LogP   0.4441
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Cyclobutylpiperazine sigma1-Cyclobutylpiperazine manufacturer1-Cyclobutylpiperazine price1-Cyclobutylpiperazine structure1-Cyclobutylpiperazine SDSbuy 1-Cyclobutylpiperazine1-Cyclobutylpiperazine supplier1-Cyclobutylpiperazine uses1-Cyclobutylpiperazine molecular weightprice of 1-Cyclobutylpiperazine1-Cyclobutylpiperazine chemical name formula of 1-Cyclobutylpiperazine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label