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CS-W001157 4
Total: USD 88.00

1,3-Diethyl 2-ethylpropanedioate

  • CAS No. 133-13-1

  • Cat. No. CS-0075087
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1,3-Diethyl 2-ethylpropanedioate|CS-0075087

Structure of 133-13-1

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Description

1,3-Diethyl 2-ethylpropanedioate is a sterically hindered diester featuring two ethyl-substituted ester groups flanking a central carbon bearing an additional ethyl moiety. This structural arrangement imparts enhanced stability and controlled reactivity, enabling its use in asymmetric synthesis and as a building block for complex heterocycles under mild conditions.

Application

1,3-Diethyl 2-ethylpropanedioate serves as a versatile β-keto ester building block in synthetic organic chemistry, enabling efficient aldol condensations and Michael additions. Its ethyl-substituted α-carbon enhances steric control in asymmetric synthesis, while the diester functionality supports facile hydrolysis and decarboxylation sequences. The compound exhibits good bench stability and is compatible with standard purification protocols, making it a practical reagent for constructing complex carbocyclic and heterocyclic scaffolds in medicinal chemistry and process development.

General Information

  • CAS No. 133-13-1
  • Cat. No. CS-0075087
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₆O₄
  • Molecular Weight 188.22
  • Synonym(s) Ethylpropanedioic acid diethyl ester
  • SMILES O=C(OCC)C(CC)C(OCC)=O

Computational Chemistry Data

  • TPSA   52.6
  • LogP   1.1388
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

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