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Structure of 133047-17-3
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(E)-3-(Thiazol-4-yl)acrylic acid features a conjugated enoic acid system linked to a thiazole heterocycle, delivering enhanced electronic delocalization and structural rigidity. This configuration supports its role in synthesizing bioactive heterocycles and functional materials, particularly where planar, electron-deficient architectures are required. The compound exhibits stability under standard handling conditions and integrates readily into cross-coupling and cycloaddition workflows.
(E)-3-(Thiazol-4-yl)acrylic acid serves as a versatile building block for the synthesis of thiazole-containing pharmaceuticals and bioactive heterocycles. Its conjugated enoic acid functionality enables efficient Michael additions, Diels-Alder reactions, and palladium-catalyzed coupling processes. The molecule exhibits good bench stability and facilitates straightforward purification via recrystallization, making it well-suited for scalable medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: